Welcome to LoneStar Heart, Inc.

LoneStar Heart, Inc. is a Texas and California based biomedical company developing new therapies to preserve and restore adequate heart function in patients with Advanced Heart Failure (HF). Based on its integrated cardiomechanical and biomolecular technologies, the privately held company is developing a broad portfolio of products to restore the failing heart’s structure and function in collaboration with the Texas Heart Institute, the University of Texas Southwestern Medical Center, and a global network of leading clinicians. These products include Algisyl-LVR™, small molecule cardiac stem-cell modulators, and cellular and genetic therapies delivered as stand-alone treatments, or in combination with the company’s proprietary biopolymer matrix system. LoneStar Heart’s lead product, Algisyl-LVR, is a single-use, self-gelling biopolymer implanted into the heart’s left ventricle during surgery. Providing internal tissue support, Algisyl-LVR is aimed at preventing the progression of heart failure and restoring the heart’s normal structure and function with a significant improvement in the patient’s quality of life. Classified as a medical device, the product is undergoing a randomized controlled clinical study (AUGMENT-HF) in Europe to evaluate its safety and efficacy in patients with advanced heart failure.